That question reeks of someone who will never. But let me offer respite.
Innovation can be separated into two major categories, upstream and downstream. Downstream innovation acts and reiterates on the supposition of a pre-established truth.
Upstream innovation disproves the truth by offering a better and higher normalization of said truth. One that subsequently induces new instances of downstream. Many iterations of downstream will deplete the economics of its viability, and consequently, offer new impetus for upstream. A process of endless perpetuity as derived from the evolution of evolution. For more information, read an in-depth article on that exact topic.
So, to answer your question, if you deem all viable economics of downstream to be depleted, it must be high time for a new normalization of upstream.
To invent such normalization, you cannot be a student schooled by the populism of hindsight. Instead, you must have the hutzpah to deal with the discovery and dogged pursuit of unprecedented foresight that breaks the norm. Such requires a cynical person, unaccepting of the aging promises of past truths. Unaccepting of the world the way it is, in hot pursuit of the way it must be. And in JFK’s words: an idealist without illusion.
Hope that helps.